汤煜春，医学博士，美国加州大学洛杉矶分校访问学者，南加州大学神经影像与信息学系博士后、Research Associate。现为山东大学基础医学院解剖学与神经生物学系副主任，教授、博士生导师，齐鲁医学院科研与国际交流办公室副主任兼山东大学国际事务部副部长，兼任中国解剖学会断层影像解剖学分会副主任委员、智慧解剖学分会常务委员、科普工作委员会常务委员、青年工作委员会常务委员，中华医学会数字医学分会青年委员，山东解剖学会常务副理事长。先后主持国家自然科学基金和省部级科研项目9项，参与美国国立卫生研究院（NIH）和国家自然科学基金项目10余项，作为主要成员获国家级教学成果奖二等奖和山东省教学成果特等奖各1项，山东省科学技术进步奖二等奖1项（第二位），中国解剖学会第二届“李继硕教授青年优秀论文奖”和第二届山东解剖学会齐鲁杰出青年解剖学者奖。 在NeuroImage和Cerebral Cortex等专业顶级期刊发表SCI论文60余篇，多次在OHBM和IFAA等国际会议做口头报告和展板演示。担任《digital medicine》和《解剖学报》等杂志编委。

 

研究兴趣

断层影像解剖学、神经影像学、数字人体及智慧解剖、计算神经科学、脑科学、神经精神疾病的影像学研究

主要学习经历

1997.09-2002.07 山东大学医学院临床医学专业 医学学士

2004.09-2009.12 山东大学医学院人体解剖与组织胚胎学专业 医学博士（硕博连读）

主要工作经历

2002.07-2004.07 山东大学机械工程学院 学生政治辅导员

2008.03-2009.02 美国加州大学洛杉矶分校 国家公派访问学者

2010.01-2012.07 山东大学齐鲁医院 神经外科博士后

2010.01-2017.09 山东大学医学院 讲师、硕导

2015.10-2017.10 美国南加州大学 博士后，Research Associate

2017.09-至今 山东大学基础医学院  副教授、教授、博导、系副主任

2018.07-2020.10 山东大学基础医学院 院长助理

2020.10-至今 山东大学 齐鲁医学院科研与国际交流办公室副

主任兼国际事务部副部长

 

主持科研项目

1. 国家自然科学基金面上项目，蓝斑-内嗅皮质-海马神经环路在阿尔茨海默病早期进程中的改变及其机制的多模态多尺度研究。

2. 国家自然科学基金面上项目，脑干白质纤维连接的概率性图谱。

3. 国家自然科学基金青年科学基金项目，中国人大脑白质的两性异形及其与认知功能的关系

4. 高等学校博士学科点专项科研基金，中国人大脑白质的男、女异型研究，

5. 山东省优秀中青年科学家科研奖励基金项目，中老年人数字化脑图谱的建立及其应用

6. 中国博士后科学基金, 中国人大脑白质的两性异形

7. 山东省博士后专项资助项目，中国老年人数字化脑图谱的建立及其应用

8. 山东大学，断层解剖学教学方法探索

 

参与国家级科研项目

1.国家自然科学基金面上项目，结构脑网络组的出生前发育与可视化（第2位）

2.国家自然科学基金面上项目，大脑皮质折叠的早期形态发生（第2位）

3.国家自然科学基金面上项目，注意网络的影像遗传学研究（第2位）

4.国家自然科学基金面上项目，人类胚胎脊柱及脊髓发育MRI与组织学对照研究（第2位）

5.国家自然科学基金面上项目， NP65在认知功能及轻度认知障碍中的作用与机制的研究（第2位）

6.国家自然科学基金青年科学基金项目，胎儿海马结构的半球间不对称性与性别二态性（第3位）

7.国家自然科学基金青年科学基金项目，遗传与环境因素对青少年脑沟形态影响及其性别差异的双生子影像学研究（第3位）

8.国家自然科学基金面上项目，大脑皮质生前发育的性别二态性（第4位）

9.国家自然科学基金青年科学基金项目，帕金森猫模型大脑皮质功能改变及其机制研究（第2位）

10.国家自然科学基金面上项目，中国人大脑皮质男、女异型研究（第4位）

11.国家自然科学基金面上项目，中国人数字化标准脑图谱系统（第4位）

 

发表论文

1. Minqi Hu, Yunxia Lou, Caiting Zhu, Jiachen Chen, Shizhou Liu, Yongfeng Liang, Shuwei Liu, Yuchun Tang*. Evaluating the impact of intracranial volume correction approaches on the quantification of intracranial structures in MRI: a systematic analysis. Journal of Magnetic Resonance Imaging, 2024.

2. Minqi Hu, Feifei Xu, Shizhou Liu, Yuan Yao, Qing Xia, Caiting Zhu ,Xinwen Zhang, Haiyan Tang, Zubair Qaiser, Shuwei Liu, Yuchun Tang*. Aging pattern of the brainstem based on volumetric measurement and optimized surface shape analysis. Brain Imaging and Behavior. 2024.

3. Wang Wenjun, Yu Qiaowen, Liang Wenjia, Xu Feifei, Li Zhuoran, Tang Yuchun*, Liu Shuwei*. Altered Cortical Microstructure in Preterm Infants at Term-equivalent Age Relative to Term-born Neonates. Cerebral Cortex, 2023, 33(3): 651-662.

4. Zhao Xiaotian, Liang Wenjia, Wang Wenjun, Liu Hailan, Zhang Xiaolei, Liu Chengxin, Zhu Caiting, Cui Baoxia, Tang Yuchun*, Liu Shuwei*. Changes in and asymmetry of the proteome in the human fetal frontal lobe during early development. Communications Biology, 2022, 29 (5):1031.

5. Liang Wenjia, Yu Qiaowen, Wang Wenjun, Thijs Dhollander, Emmaneul Suluba, Li Zhuoran, Xu Feifei, Hu Yang, Tang Yuchun*, Liu Shuwei*. A comparative study of the superior longitudinal fasciculus subdivision between neonates and young adults. Brain Structure and Function, 2022, 227(8): 2713-2730.

6. Sun Wei#, Tang Yuchun#, Qiao Yuchuan#, Ge Xinting, Mara Mather, John M. Ringman, Shi Yonggang, for Alzheimer’s Disease Neuroimaging Initiative. A probabilistic atlas of locus coeruleus pathways to transentorhinal cortex for connectome imaging in Alzheimer's disease. NeuroImage, 2020, 223: 117301.

7. Lou Yunxia, Zhao Lu, Yu Shui, Sun Bo, Hou Zhongyu, Zhang Zhonghe, Tang Yuchun*, Liu Shuwei. Brain asymmetry differences between Chinese and Caucasian populations: a surface-based morphometry comparison study. Brain Imaging and Behavior, 2020, 14:2323-2332.

8. Tang Yuchun*, Zhao Lu, Lou Yunxia, Shi Yonggang, Fang Rui, Lin Xiangtao, Liu Shuwei, Arthur Toga. Brain structure differences between Chinese and Caucasian cohorts: A comprehensive morphometry study. Human Brain Mapping, 2018, 39(5): 2147-2155.

9. Tang Yuchun#, Sun Wei#, Arthur Toga, Ringman JM, Shi Yonggang. A probabilistic atlas of human brainstem pathways based on connectome imaging data. Neuroimage, 2018, 169: 227~239.

10. Amuti Siyiti#, Tang Yuchun#, Wu Shuang, Liu, Lifen, Huang Liang, Zhang Haibo, Li Huanhuan, Jiang, Fen, Wang Geying, Liu Xiaoqing, Yuan Qionglan. Neuroplastin 65 mediates cognitive functions via excitatory/inhibitory synapse imbalance and ERK signal pathway. Neurobiol Learn Mem. 2016, 127: 72-83.

11. Tang Y, Hojatkashani C., Dinov I.D., Sun B, Fang L, Lin X, Qi H, Hua X, Liu S, Toga A.W..The construction of a Chinese MRI brain atlas: A morphometric comparison study between Chinese and Caucasian cohorts. Neuroimage. 2010.51:33-41.

12. Tang Y, Zhao Z, Lin X, Sun B, Fan L, Hou Z，Qi H, Li Z, Liu S. The thin sectional anatomy of the sellar region with MRI correlation. Surg Radiol Anat. 2010,32 (6):573-80.

13. Tang Y, Bai X, Yang X，Lin L, Liu S, Latecki, L.J.. Skeletonization with particle filters. Int J Pattern Recogn. 2010,24(4):619-34.

14. Tian Mimi, Xu Feifei, Xia Qing, Tang Yuchun, Zhang Zhonghe, Lin Xiangtao, Meng Haiwei, Feng Lei, Liu Shuwei. Morphological development of the human fetal striatum during the second trimester. Cerebral Cortex. 2022, 32(22):5072-5082.

15. Wang Yu, Xu Feiei, Zhou Wenjuan, Hou Lanwei, Tang Yuchun, Liu Shuwei. Morphological and hemispheric and sex differences of the anterior ascending ramus and the horizontal ascending ramus of the lateral sulcus. 2022, 227(6): 1949-1961.

16. Xu, Feifei, Liu, Mengting, Kim, Sharon Y., Ge, Xinting, Zhang, Zhonghe, Tang, Yuchun, Lin, Xiangtao, Toga, Arthur W., Liu, Shuwei, Kim, Hosung. Morphological Development Trajectory and Structural Covariance Network of the Human Fetal Cortical Plate during the Early Second Trimester, Cerebral Cortex, 2021, 31(10)：4794-4807.

17. Xiao, Min, Ge, Haitao, Khundrakpam, Budhachandra S., Xu, Junhai, Bezgin, Gleb, Leng, Yuan, Zhao, Lu, Tang, Yuchun, Ge, Xinting, Jeon, Seun, Xu, Wenjian, Evans, Alan C., Liu, Shuwei. Attention Performance Measured by Attention Network Test Is Correlated with Global and Regional Efficiency of Structural Brain Networks. Frontiers in Behavioral Neuroscience, 2016,10:194.

18. Leng, Yuan, Shi, Yonggang, Yu, Qiaowen, Van Horn, John Darrell, Tang, Haiyan, Li, Junning, Xu, Wenjian, Ge, Xinting, Tang, Yuchun, Han, Yan, Zhang, Dong, Xiao, Min, Zhang, Huaqiang, Pang, Zengchang, Toga, Arthur W., Liu, Shuwei. Phenotypic and Genetic Correlations Between the Lobar Segments of the Inferior Fronto-occipital Fasciculus and Attention. Scientific Reports, 2016, 6: 33015-33015.

19. Xinting Ge, Yonggang Shi, Junning Li, Zhonghe Zhang, Xiangtao Lin, Jinfeng Zhan, Haitao Ge, Junhai Xu, Qiaowen Yu, Yuan Leng, Gaojun Teng, Lei Feng, Haiwei Meng, Yuchun Tang, Fengchao Zang, Arthur Toga, Shuwei Liu. Development of the human fetal hippocampal formation during early second trimester. NeuroImage, 2015, 119: 33~43.

20. Xu J, Yin X, Ge H, Han Y, Pang Z, Tang Y, Liu B, Liu S. Attention performance is correlated with the local regional efficiency of intrinsic brain networks. Front Behav Neurosci. 2015, 9:200.

21. Sun B, Ge H, Tang Y, Hou Z, Xu J, Lin X, Liu S. Asymmetries of the central sulcus in young adults: Effects of gender, age and sulcal pattern. Int J Dev Neurosci. 2015, 44: 65-74.

22. Xu J, Rees G, Yin X, Song C, Han Y, Ge H, Pang Z, Xu W, Tang Y, Friston K, Liu S. Spontaneous neuronal activity predicts intersubject variations in executive control of attention. Neuroscience, 2014, 263:181-92.

23. Liu C, Tang Y, Ge H, Wang F, Sun H, Meng H, Wang S, Xu J, Fan R, Fan L, Zhang Z, Shan T, Yuan H, Zhan J, Yu Q, Ge X, Tang H, Leng Y, Ding S, Liu S. Increasing breadth of the frontal lobe but decreasing height of the human brain between two Chinese samples from a Neolithic site and from living humans. Am J Phys Anthropol, 2014, 154(1):94-103.

24. Lou L, Liu SW, Zhao ZM, Tang YC, Lin XT. Acquisition of thin coronal sectional dataset of cadaveric liver. Surg Radiol Anat, 2014, 36(3):225-9.

25. Zhan, Jinfeng; Dinov, Ivo D.; Li, Junning; Zhang, Zhonghe; Hobel, Sam; Shi, Yonggang; Lin, Xiangtao; Zamanyan, Alen; Feng, Lei; Teng, Gaojun; Fang, Fang; Tang, Yuchun; Zang, Fengchao; Toga, Arthur W. ; Liu, Shuwei ,Spatialtemporal atlas of human fetal brain development during the early second trimester , Neuroimage, 2013. 82: 115~126.

26. Ge H, Yin X, Xu J, Tang Y, Han Y, Xu W, Pang Z, Meng H, Liu S. Fiber pathways of attention subnetworks revealed with tract-based spatial statistics (TBSS) and probabilistic tractography. PloS One, 2013, 8(11): e78831.

27. Zhang ZH, Meng HW, Hou ZY, Ma J, Feng L, Lin XT, Tang YC, Zhang XL, Liu QW, Liu SW. Fetal Adrenal Gland in the Second Half of Gestation: Morphometrical Assessment with 3.0T Post-Mortem MRI. PloS One, 2013. 8(10): e75511.

28. Yin X, Zhao L, Xu J, Evans AC, Fan L, Ge H, Tang Y, Khundrakpam B, Wang J, Liu S. Anatomical substrates of the alerting, orienting and executive control components of attention: focus on the posterior parietal lobe. Plos One, 2012,7 (11):e50590.

29. Liu J, Liu S, Heng X, Fei C, Wei Y, Zhang J, Zhang Z, Tang Y. The Values of thin sections and three-dimensional reconstruction in the sellar region. World Neurosurgery, 2012, 78(5): 510-515.

30. Tang Y, Liu S, Sun B, Fan L, Lin X. Research progress of the digital human brain atlas. China Digital Medicine, 2012, 7(1):21-24.

31. Tang Y, Hojatkashani C., Dinov I.D., Sun B, Fang L, Lin X, Qi H, Hua X, Liu S, Toga A.W..The construction of a Chinese MRI brain atlas: A morphometric comparison study between Chinese and Caucasian cohorts. Neuroimage. 2010.51:33-41.

32. Fang L, Tang Y, Sun B,Gong G, Zhang J, Lin X, Yu T, Li Z, Alan C.Evans,Liu S.Sexual dimorphism and asymmetry in human cerebellum: A MRI-based morphometric study. Brain Res. 2010, 1353:60-73.

33. Lin X, Tang Y, Sun B, Hou Z, Meng H, Li Z, Liu Q, Liu S. Cerebral glucose metabolism: Influence on perihematomal edema formation after intracerebral hemorrhage in cat models. Acta Radiol, 2010, 51(5):549-54.

34. Wang H, Ding J, Sun B, Lin X, Ge H, Tang Y, Li Z, Liu S. Three-dimensional MRI study on the morphology and lateral asymmetry of Chinese female calcarine sulcus. ACTA ANATOMICA SINICA, 2010, 41(2): 285-290.

35. Sun B, Wang D, Tang Y, Fan L, Lin X, Yu T, Qi H, Li Z, Liu S. The pineal volume: a three-dimensional volumetric study in healthy young adults using 3.0T MR data. Int J Dev Neurosci. 2009, 27(7):655-560.

36. Lou L, Liu S, Zhao Z, Heng P, Tang Y, Li Z, Xie Y, Chui Y. Segmentation and reconstruction of hepatic veins and intrahepatic portal vein based on the coronal sectional anatomic dataset. Surg Radiol Anat. 2009, 31(10):763-768.

37. Tang Y, Liu S, Zhao Z, Lin X, Li Z, Yin Q. Thin transverse sectional anatomy of the sellar region with corresponding MRI. ACTA ANATOMICA SINICA, 2009, 40(1): 159-161.

38. Sun B, Liu S, Tang Y, Fan L, Lin X, Li Z, Qi H. Contrasted study between thin coronal sectional anatomy of the pineal region and MRI image. ACTA ANATOMICA SINICA, 2009, 40(4): 679-684.

39. Fan L, Liu S, Tang Y, Sun B, Lin X, Li Z, Qi H. Comparative study between thin transverse sectional anatomy and magnetic resonance imaging of deep nuclei in human cerebellum. ACTA ANATOMICA SINICA, 2009, 40(2): 317-322.

40. Chen C, Liu S, Lin X, Tang Y, Hou Z, Wang Z, Li Z, Yin Q. Sectional anatomy of human optic pathways on the coronal plane. ACTA ANATOMICA SINICA, 2009, 40(2): 323-327.

41. Sun B, Tang Y, Fan L, Lin X, Li Z, Qi H, Liu S. The pineal region: thin sectional anatomy with MR correlation in the coronal plane. Surg Radiol Anat. 2008, 30 (7):575-582.

42. Ma G, Liu S, Zhao Z, Lin X, Lou L, Li Z, Tang Y, Zhong S. Sectional anatomy of the adrenal gland in the coronal plane. Surg Radiol Anat. 2008, 30(3):271-280.

国际会议报告

1. Tang Yuchun, Brain structure differences between Chinese and Caucasian cohorts: a morphometry study. 19th Congress of International Federation of Association of Anatomists (IFAA2019), London, UK, 2019.8.9-2019.8.11.

2. Tang Yuchun, Zhao Lu, Lou Yunxia, Shi Yonggang, Fang Rui, Lin Xiangtao, Liu Shuwei, Arthur Toga. Brain Structure differences between Chinese and Caucasian cohorts: a comprehensive morphometry study. 24th Annual Meeting of the Organization for Human Brain Mapping, Singapore, 2018.6.17-2.18.6.21.

3. Tang Yuchun, Sun Wei, Arthur Toga, Ringman JM, Shi Yonggang. An atlas of brainstem connectomes from HCP data. 23th Annual Meeting of the Organization for Human Brain Mapping, Vancouver, Canada, 2017.6.25-2017.6.29.

4. Tang Yuchun, Zhan Jinfeng, Liu Shuwei. Spatial-temporal atlas of fetal brain development during the early second trimester. 19th Annual Meeting of the Organization for Human Brain Mapping, Seattle, Washington, USA, 2013.6.16-2013.6.20.

5. Tang Yuchun, Liushuwei. The construction of Chinese brain atlas. 18th Congress of International Federation of Association of Anatomists (IFAA2014), Beijing, China, 2014.8.8-2014.8.10

 

奖励情况

1. 2018.12 我国数字解剖学教学体系创建与推广，国家级教学成果奖二等奖

2，2018.08 第二届山东解剖学会齐鲁杰出青年解剖学者奖

3，2018.08 山东解剖学会2018年度优秀论文一等奖

4. 2018.03 中国人数字化标准脑图谱的创建与推广应用，山东省科学技术进步奖二等奖

5.  2018.01 我国数字解剖学教学体系创建与推广，山东省省级教学成果奖特等奖

6.  2012.07 The construction of a Chinese MRI brain atlas: a morphometric comparison study between Chinese and Caucasian cohorts, 山东解剖学会, 山东解剖学会青年优秀论文奖一等奖。

7.  2010.10 The construction of a Chinese MRI brain atlas: a morphometric comparison study between Chinese and Caucasian cohorts. 中国解剖学会第二届“李继硕教授青年优秀论文奖” 。

8.  2014.07 断层影像解剖学教学资源创建与推广应用，山东省教学成果奖二等奖。