周文娟，医学博士，山东大学基础医学院解剖与神经生物学系副教授，硕士生导师，中国科协青年人才托举工程入选者。科研方向：长期从事神经干细胞发育及神经系统发育相关疾病等调控机制和干细胞治疗研究，在Advanced functional materials、Cell Death & Disease、Stem Cell Research & Therapy、Translational Psychiatry、Cerebral Cortex、Journal of affective disorders等杂志发表多篇SCI论文。目前担任中国解剖学会第十七届理事会青年工作委员会委员，山东省医师协会神经修复学专业委员会委员。

教育及工作经历

2023-09至今，山东大学，基础医学院，副教授

2019-08至2023-08，山东大学，基础医学院，助理研究员

2015-09至2019-07，山东大学，人体解剖与组织胚胎学系，博士

2012-09至2015-07，山东大学，神经生物学系，硕士

2008-09至2012-07，山东师范大学，生物科学系，学士

代表性论著

1. He Xia^#; Wenjuan Zhou^#; Dezheng Li; Fan Peng; Liyang Yu; Yuanhua Sang; Hong Liu*; Aijun Hao*; Jichuan Qiu*; Generation of a Hydrophobic Protrusion on Nanoparticles to Improve the Membrane‐Anchoring Ability and Cellular Internalization, Angewandte Chemie International Edition. 2024, 63(9)

2. Liang Wang^#, Wenjuan Zhou^#, Hongru Yang^#, Feng Liu, Ying Kong, Wenhan Wang, Hang Zhao, Wenjun Ma, Yuanhua Sang, Fan Yi, Hong Liu*, Chao Liu*, Aijun Hao* and Jichuan Qiu*. Calcium Folate Nanoparticles as Dual-Functional Neural Inducing Factors to Promote the Differentiation of Neural Stem Cells into Cholinergic Neurons. Advanced functional materials. 2023

3. TianTian Zhao, Dongshuang Wang, Dong Wu, Jingyi Du, Man Zhao, Fan Peng, Meihua Zhang, Wenjuan Zhou*, Aijun Hao*. Astilbin attenuates neonatal postnatal immune activation-induced long-lasting cognitive impairment in adult mice. Journal of Functional Foods. 2023, 102, 105434.

4. Yuan Yao, Lajie Man, Jingyi Du, Dong Wu, Liping Yang, Fan Peng, Lei Han, TianTian Zhao*, Wenjuan Zhou*. Astilbin ameliorates depressive-like behavior caused by postnatal immune activation through Menin-regulated astrocyte inflammation. Journal of affective disorders. 2022 Mar 15; 301: 87-98.

5.TianTian Zhao, Dong Wu, Jingyi Du, Guowei Liu, Guangyu Ji, Zixiao Wang, Fan Peng, Lajie Man, Wenjuan Zhou*, Aijun Hao*. Folic Acid Attenuates Glial Activation in Neonatal Mice and Improves Adult Mood Disorders Through Epigenetic Regulation. Front Pharmacol. 2022 Feb 7;13:818423.

6. Xinyue Li, Guangyu Ji, Juan Zhou, Jingyi Du, Xian Li, Wei Shi, Yong Hu, Wenjuan Zhou*, Aijun Hao*. Pcgf1 regulates early neural tube development through histone methylation in zebrafish. Frontiers in cell and developmental biology. 2021 Jan 26:8:581636

7. Man Zhao, Yuan Yao, Jingyi Du, Liang Kong, Tiantian Zhao, Dong Wu, Lajie Man, Wenjuan Zhou*. 6-Gingerol Alleviates Neonatal Hypoxic-Ischemic Cerebral and White Matter Injury and Contributes to Functional Recovery. Frontiers in pharmacology. 2021 Sep 22. 12:707772.

8. Wenjuan Zhou, Tiantian Zhao, Jingyi Du, Guangyu Ji, Xinyue Li, Shufang Ji, Wenyu Tian, Xu Wang, Aijun Hao*. TIGAR promotes neural stem cell differentiation through acetyl-CoA-mediated histone acetylation, Cell Death & Disease. 2019 Feb 27;10(3):198.

9. Xian Li^#, Wenjuan Zhou^#, Xinyue Li, Ming Gao, Shufang Ji, Wenyu Tian, Guangyu Ji, Jingyi Du, Aijun Hao*. SOX19b regulates the premature neuronal differentiation of neural stem cells through EZH2-mediated histone methylation in neural tube development of zebrafish, Stem Cell Research & Therapy. 2019 Dec 16;10(1):389.

10. Wenjuan Zhou, Yuan Yao, Jinxing Li, Dong Wu, Man Zhao, Zongting Yan, Aimei Pang, Liang Kong*. TIGAR attenuates high glucose-induced neuronal apoptosis via an autophagy pathway. Frontiers in molecular neuroscience. 2019 Aug 13; 12: 193.

11. Wenjuan Zhou^#, Ning Xu^#, Liang Kong, Shicheng Sun, Xufeng Xu, Mingzhong Jia, Yue Wang*, Zheyu Chen*. The antidepressant roles of Wnt2 and Wnt3 in stress-induced depression-like behaviors. Translational Psychiatry. 2016 Sep 13;6(9):e892.

主持科研项目

1.国家自然科学基金青年科学基金项目,TOX3对海马发育的调控作用和机制研究,2021-01-01 至 2023-12-31, 24万元, 主持

2.中国科学技术协会“青年人才托举工程”，2020-01 至 2022-12,45万元,主持

3.山东省自然科学基金青年科学基金项目,TOX3调控海马神经干细胞增殖分化的新发现和机制研究,2021-01至2023-12,15万元，主持